Molecular Phenotyping Core Laboratory (MPCL)

The Molecular Phenotyping Core Laboratory (MPCL) at the Centre for Heart Lung Innovation (HLI) is a fee-for-service, multi-user laboratory. The MPCL provides research tools and technical support to researchers and clinicians both within the HLI and Providence Health Care as well as external groups from the Lower Mainland research community and beyond.

Evolving from the fusion of the Flow Cytometry and Genotyping laboratories, and expanded by funding from the Canada Foundation for Innovation, the MPCL provides a unique environment for the complete characterization of biological samples. Members of the MPCL are involved in studies of cell phenotyping, protein profiling, genotyping and gene expression in order to further our understanding of the pathogenesis of cardiovascular, respiratory and systemic inflammatory diseases including transplant rejection, asthma and COPD.

The MPCL consists of five integrated areas of focus:

• flow cytometry
• genotyping
• RNA analysis
• multiplex protein analyses
• Biobanking

These core areas of focus combined with our specialized staff create an enhanced environment of synergy. This ultimately leads to a greater understanding of cardiovascular and pulmonary diseases that can be effectively translated into improved patient care.

Our technicians have extensive training on all our equipment and can help with all stages of your project, from planning and experimental design, to hands-on advice, troubleshooting and data analysis. They also provide technology seminars and one-on-one or group training sessions. All technology, with the exception of the Astrios EQ, can be user operated following training. Please contact the Molecular Phenotyping Core Laboratory for additional information including pricing. The MPCL is located on the 2nd floor of the Burrard Building at St. Paul’s Hospital, Room 292. Please feel free to drop by to discuss your project requirements.